• An In Vitro Dosimetry Tool for the Numerical Transport Modeling of Engineered Nanomaterials Powered by the Enalos RiskGONE Cloud Platform 

      Cheimarios, Nikolaos; Pem, Barbara; Tsoumanis, Andreas; Ilic, Krunoslav; Vrček, Ivana Vinković; Melagraki, Georgia; Bitounis, Dimitrios; Isigonis, Panagiotis; Dusinska, Maria; Lynch, Iseult; Demokritou, Philip; Afantitis, Antreas (Peer reviewed; Journal article, 2022)
      A freely available “in vitro dosimetry” web application is presented enabling users to predict the concentration of nanomaterials reaching the cell surface, and therefore available for attachment and internalization, from ...
    • Linking Nanomaterial-Induced Mitochondrial Dysfunction to Existing Adverse Outcome Pathways for Chemicals 

      Murugadoss, Sivakumar; Vrček, Ivana Vinković; Schaffert, Alexandra; Paparella, Martin; Pem, Barbara; Sosnowska, Anita; Stępnik, Maciej; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Cimpan, Mihaela-Roxana; Lemaire, Frauke; Mertens, Birgit; Dusinska, Maria; Fessard, Valérie; Hoet, Peter H. (Peer reviewed; Journal article, 2023)
      The Adverse Outcome Pathway (AOP) framework plays a crucial role in the paradigm shift of toxicity testing towards the development and use of new approach methodologies. AOPs developed for chemicals are in theory applicable ...
    • A strategy towards the generation of testable adverse outcome pathways for nanomaterials 

      Murugadoss, Sivakumar; Vrcek, Ivana Vinkovic; Pem, Barbara; Jagiello, Karolina; Judzinska, Beata; Sosnowska, Anita; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Dusinska, Maria; Cimpan, Mihaela-Roxana; Fessard, Valérie; Hoet, Peter H. (Peer reviewed; Journal article, 2021)
      Manufactured nanomaterials (NMs) are increasingly used in a wide range of industrial applications leading to a constant increase in the market size of nano-enabled products. The increased production and use of NMs are ...